abstract：:We investigated a possible relationship between brefeldin A (BFA), an antibiotic, and cathepsin D (Cat.D), a lysosomal protease, in prostate cancer proliferation. Effects of BFA (30 ng/ml) were examined on the growth of three human prostatic cancer cell lines, PC-3, DU-145, and LNCaP cells. Its effect on Cat.D in thes...

journal_title：World journal of urology

authors： Konno S,Cherry JP,Mordente JA,Chapman JR,Choudhury MS,Mallouh C,Tazaki H

更新日期：2001-08-01 00:00:00

abstract：:The effects of pelvic floor muscle contraction on rectal and vesical function were studied in 19 healthy volunteers with the aim of shedding light on some of the hitherto vague aspects of the mechanisms involved in micturition and defecation and their disorders. Rectal and vesical pressures were recorded during pubore...

journal_title：World journal of urology

authors： Shafik A,El-Sibai O

更新日期：2001-08-01 00:00:00

abstract：:A Persian Gulf War veteran presented to the University Neuro-Urology service for management of severe chronic perineal pain. The overall physical and neurological exam was unremarkable. However, the rectal exam and the urodynamic study revealed a severe pelvic floor dysfunction. A neuro-behavioral approach is recommen...

journal_title：World journal of urology

authors： Zermann DH,Ishigooka M,Doggweiler-Wiygul R,Schmidt RA

更新日期：2001-06-01 00:00:00

abstract：:The purpose of this study was to assess possible central side-effects of sildenafil (Viagra) on attention and memory functions. Sildenafil and placebo were administered in young male subjects in a double-blind balanced cross-over design. Behavioral patterns and event-related brain potentials (ERP) were recorded in a s...

journal_title：World journal of urology

authors： Schultheiss D,Müller SV,Nager W,Stief CG,Schlote N,Jonas U,Asvestis C,Johannes S,Münte TF

更新日期：2001-02-01 00:00:00

abstract：:We evaluated the quality of micturition in patients with orthotopic neobladder replacement. In the present study, 58 patients who had undergone orthotopic neobladder replacement following cystectomy were enrolled. The quality of micturition was evaluated by means of uroflowmetry, a self-administered questionnaire and ...

journal_title：World journal of urology

authors： Gotoh M,Mizutani K,Furukawa T,Kinukawa T,Ono Y,Ohshima S

更新日期：2000-12-01 00:00:00

abstract：:The orthotopic neobladder has become the preferred method of handling the urinary tract after removal of the bladder in men and women. However, an improved quality of life compared to urinary diversion fails to be realized when voiding dysfunction arises. These difficulties with urination range from retention to incon...

journal_title：World journal of urology

authors： Steers WD

更新日期：2000-10-01 00:00:00

abstract：:Renal cystic disease, ranging from simple cysts to autosomal dominant polycystic kidney disease (ADPKD), can lead to significant complications such as pain, hypertension, infection, upper urinary tract obstruction, and even renal failure. For patients with preserved renal function, laparoscopic ablation of renal cysts...

journal_title：World journal of urology

authors： Dunn MD,Clayman RV

更新日期：2000-09-01 00:00:00

abstract：:The purpose of the present study was to examine the outcome profiles of a large number of patients with locally advanced adenocarcinoma of the prostate following radical perineal prostatectomy (RPP) for clinically organ-confined disease. Of 1662 men who underwent RPP performed by a single surgeon between January 1972 ...

journal_title：World journal of urology

authors： Dahm P,Vieweg J,Newhall PM,Robertson JE,Paulson DF

更新日期：2000-06-01 00:00:00

abstract：:The treatment options for patients with advanced prostate cancer are limited. Because of recent advances in the understanding of the molecular biology of prostate cancer, the accessibility of the prostate for injection, and the availability of gene promotors that allow tissue-specific expression of therapeutic gene pr...

journal_title：World journal of urology

authors： Pantuck AJ,Zisman A,Belldegrun AS

更新日期：2000-04-01 00:00:00

abstract：:Small-intestinal submucosa (SIS) is a unique biomaterial that has been shown to induce tissue-specific regeneration in numerous organ systems. In the urinary tract, animal studies have demonstrated that SIS promotes functional bladder regeneration. Other preliminary studies have suggested that SIS may also be extremel...

journal_title：World journal of urology

authors： Cheng EY,Kropp BP

更新日期：2000-02-01 00:00:00

abstract：:Tissue engineering, long a matter of myth and dream throughout the history of medicine, is now a practical reality. A wide spectrum of biological materials are used in the field of urology to treat disease and to overcome human disabilities, including tissue grafts and organ transplantation. Laboratory-engineered biop...

journal_title：World journal of urology

authors： Schultheiss D,Bloom DA,Wefer J,Jonas U

更新日期：2000-02-01 00:00:00

abstract：:Serotonin (5-hydroxytryptamine; 5-HT), a vasoactive bioamine with potent contractile activity, is thought to act indirectly in the urinary bladder by the stimulation of its presynaptic receptors. This results in the release of acetylcholine (ACh), which then acts on muscarinic receptors to produce bladder contractilit...

journal_title：World journal of urology

authors： Khan MA,Dashwood MR,Thompson CS,Mumtaz FH,Morgan RJ,Mikhailidis DP

更新日期：1999-10-01 00:00:00

abstract：:The most important phosphates involved in urinary stone disease are carbonate apatite, brushite, and struvite. Overall, phosphate stones account for 12-20% of all stones, with a downward trend for struvite and an increase in carbonate apatite being observed in the last decade. The physicochemical basis for the formati...

journal_title：World journal of urology

authors： Hesse A,Heimbach D

更新日期：1999-10-01 00:00:00

abstract：:This paper provides an overview of the scientific and practical aspects of assessing health-related quality of life (HRQL). The paper provides a brief overview of developments in the field and then discusses the definition of HRQL. The different types of HRQL measure available to researchers are described, with specif...

journal_title：World journal of urology

authors： Browne JP

更新日期：1999-08-01 00:00:00

abstract：:One of the historic landmarks in urology is the first planned nephrectomy performed in 1869 by Gustav Simon of Heidelberg (1824-1877). In the history of medicine the reflections and considerations of the specialized surgeon reveal distinguished analyses of the "case" and, thus, the beginning of a modern scientific dis...

journal_title：World journal of urology

authors： Moll F,Rathert P

更新日期：1999-06-01 00:00:00

abstract：:Genital skin loss results from a heterogeneous group of traumatic and infectious processes. Removal of all devitalized tissue is necessary prior to reconstructive surgery; hyperbaric oxygen may help in the management of necrotizing infections. Defect coverage depends more on the remaining genital skin than on the etio...

journal_title：World journal of urology

authors： Wessells H

更新日期：1999-04-01 00:00:00

abstract：:We are fortunate that our ability to diagnose the specific adrenal entities that mandate a surgical approach is extremely accurate. The combination of analytical methodology to measure the appropriate adrenocortical and medullary hormone production and the radiology techniques for localization are superb. The manageme...

journal_title：World journal of urology

authors： Vaughan ED Jr

更新日期：1999-02-01 00:00:00

abstract：:The aim of this study was to determine the long-term clinical efficacy and complications of neuromodulation with a unilateral sacral foramen electrode in 36 patients with chronic voiding dysfunction. Following a positive effect of a percutaneous nerve evaluation test, patients underwent open surgery. A permanent elect...

journal_title：World journal of urology

authors： Weil EH,Ruiz-Cerdá JL,Eerdmans PH,Janknegt RA,Van Kerrebroeck PE

更新日期：1998-01-01 00:00:00

abstract：:Ileal conduits have long been accepted as a standard method for urinary diversion, but conventional ileal conduits are not always suitable for patients whose ureters are for the greater part compromised by neoplasm or preoperative irradiation, resulting in a shortening of the ureters. Bowel migration into the large ca...

journal_title：World journal of urology

authors： Hatano T,Hayakawa M,Koyama Y,Sugaya K,Miyazato T,Ogawa Y

更新日期：1998-01-01 00:00:00

abstract：:Telemedicine is the use of communication technologies to deliver health care. Telesurgical telementoring represents an advanced form of telemedicine, whereby an experienced surgeon can guide and teach practicing surgeons new operative techniques utilizing current video technology, medical robots, and high-band-width t...

journal_title：World journal of urology

authors： Lee BR,Bishoff JT,Janetschek G,Bunyaratevej P,Kamolpronwijit W,Cadeddu JA,Ratchanon S,O'Kelley S,Kavoussi LR

更新日期：1998-01-01 00:00:00

abstract：:This study was designed to evaluate the impact of lower-energy transurethral microwave thermotherapy (TUMT) on quality of life (QoL) and quality of sexual function (QSF) in patients with benign prostatic hyperplasia (BPH). A total of 216 patients with BPH received lower-energy TUMT treatment (Prostasoft 2.0) and were ...

journal_title：World journal of urology

authors： Francisca E,Blute M,de la Rosette J

更新日期：1998-01-01 00:00:00

abstract：:The use of intestinal segments in genitourinary reconstruction could influence vitamin metabolism and affect the skeletal bone and its mineral content in the long term. In 137 patients, serum levels of the vitamins A, B1, B2, B6, B12, D, and E and of folic acid, bile acid, and ammonia as well as levels of intracorpusc...

journal_title：World journal of urology

authors： Stein R,Lotz J,Andreas J,Fisch M,Prellwitz W,Hohenfellner R,Thüroff JW

更新日期：1998-01-01 00:00:00

abstract：:With the advantages of constant availability, minimal loss of bowel, relative simplicity (no mesentery interfering with implantation, high mobility of the tube), minimized risk of stone formation (no use of staples), reliable continence (no leak point) and easy catheterization (longitudinal folds), this straightforwar...

journal_title：World journal of urology

authors： Gerharz EW,Woodhouse CR

更新日期：1998-01-01 00:00:00

abstract：:Reconstruction of long anterior urethral strictures that cannot be excised and reanastomosed remains controversial. We critically reviewed the literature on free-graft and pedicled skin-flap urethroplasty to determine the optimal method of repair. Overall, free grafts were successful in 84.3% of cases and flaps, in 85...

journal_title：World journal of urology

authors： Wessells H,McAninch JW

更新日期：1998-01-01 00:00:00

abstract：:Noncontrast helical computed tomography (CT) has recently been found to be superior to excretory urography (IVU) in the evaluation of patients with suspected ureterolithiasis. Noncontrast helical CT does not require the use of intravenous contrast material with its associated cost and risk of adverse reactions and can...

journal_title：World journal of urology

authors： Boridy IC,Nikolaidis P,Kawashima A,Sandler CM,Goldman SM

更新日期：1998-01-01 00:00:00

abstract：:Successful management of transitional-cell carcinoma of the urinary bladder is greatly dependent upon regular surveillance and early detection of persistent or recurrent carcinoma. The development of a highly sensitive urinary test for the detection of transitional-cell carcinoma of the bladder could have a dramatic i...

journal_title：World journal of urology

authors： Shelfo SW,Soloway MS

更新日期：1997-01-01 00:00:00

abstract：:Can urolithiasis start as an intratubular event? Under severe hyperoxaluric conditions in animal models at least crystal formation can. Recently models have been presented that assess the chances of crystal formation under more normal conditions. These models describe changes in fluid composition as this passes throug...

journal_title：World journal of urology

authors： Kok DJ

更新日期：1997-01-01 00:00:00

abstract：:We constructed a pubovaginal sling using the Gore-tex Soft Tissue Patch and 2-0 polytetrafluoroethylene (PTFE) suspension suture and placed it in 122 consecutive incontinent women with urethral hypermobility and/or intrinsic sphincter deficiency. We performed a retrospective outcome analysis using a questionnaire-base...

journal_title：World journal of urology

authors： Staskin DR,Choe JM,Breslin DS

更新日期：1997-01-01 00:00:00

abstract：:A review of the current literature is conducted to explore the developmental aspects, animal and human experiences and the effects of pharmacological manipulation to explain the role androgens play in sexual function with special emphasis on erectile function and the erectile tissue. This review reveals that androgens...

journal_title：World journal of urology

authors： Shabsigh R

更新日期：1997-01-01 00:00:00

abstract：:Metastasis is the cascade of events involved in the transition of a malignancy from a localized tumor to the establishment of a distant foci. In this review we define the known stages and the factors involved. The multiplicity of steps involved allows many opportunities for therapeutic intervention. Current research h...

journal_title：World journal of urology

authors： Lawrence JA,Steeg PS

更新日期：1996-01-01 00:00:00

abstract：:Mycophenolate mofetil (MM) is the ester derivative of mycophenolic acid (MPA), which exerts immunosuppressive activity by inhibiting de novo purine biosynthesis. Following animal models and pilot studies in human renal allograft recipients that confirmed MM's ability to prevent and half rejection episodes, 3 large mul...

journal_title：World journal of urology

authors： Hodge EE

更新日期：1996-01-01 00:00:00

abstract：:Pyeloplasty for congenital ureteropelvic junction (UPJ) obstruction enjoys a 90-95% success rate. Although treatment of the failed pyeloplasty has been addressed in the literature, management of the poorly draining or nondraining renal unit in the immediate postoperative period has not received any attention. For this...

journal_title：World journal of urology

authors： Miyamoto KK,Mesrobian HG

更新日期：1996-01-01 00:00:00

abstract：:Orthotopic urinary diversion via the Kock ileal neobladder is the preferred form of bladder reconstruction in men and, now, in women undergoing cystectomy at the University of Southern California. Through June of 1993, 266 men were diverted in this fashion. There were 3 perioperative mortalities (1.1%); early complica...

journal_title：World journal of urology

authors： Elmajian DA,Stein JP,Skinner DG

更新日期：1996-01-01 00:00:00

abstract：:This is the first reported use of low-angle X-ray scattering for the investigation of urinary calculi. Low-angle X-ray scattering (LAXS) measures the diffraction of a broad spectrum of X-rays at a single angle and uses a conventional diagnostic X-ray beam, and could thus be developed for use in vivo. A total of 45 cal...

journal_title：World journal of urology

authors： Dawson C,Horrocks JA,Kwong R,Speller RD,Whitfield HN

更新日期：1996-01-01 00:00:00

abstract：:During bladder development, undifferentiated mesenchymal and epithelial cells undergo an orderly sequence of differentiation defined by the expression of smooth-muscle (alpha-actin, myosin, vinculin, desmin, vimentin, and laminin) and epithelial (cytokeratins 5, 7, 8, 14, 18 and 19) protein markers. This process requi...

journal_title：World journal of urology

authors： Baskin LS,Hayward SW,Sutherland RA,DiSandro MJ,Thomson AA,Goodman J,Cunha GR

更新日期：1996-01-01 00:00:00

abstract：:A low-pressure reservoir for urine is created by antimesenteric splitting and side-to-side anastomosis of the rectosigmoid, the expectation being to obtain better continence rates and better protection of the upper tract than are achievable by ureterosigmoidostomy. Between 1990 and August 1993 the procedure was perfor...

journal_title：World journal of urology

authors： Fisch M,Wammack R,Hohenfellner R

更新日期：1996-01-01 00:00:00

abstract：:The present discussion on the natural history, growth rate pathophysiology, morbidity, and possible treatment of benign prostatic hyperplasia (BPH) reinforces the need to objectify mechanical BPH-induced obstruction with pressure-flow study. Different methods for the quantification of BPH-induced obstruction exist and...

journal_title：World journal of urology

authors： Höfner K,Kramer AE,Tan HK,Krah H,Jonas U

更新日期：1995-01-01 00:00:00

abstract：:Growth and morphogenesis of the prostate involves mesenchymal-epithelial interactions. Transforming growth factor-beta 1 (TGF-beta1) is one growth factor that may play a role in these paracrine interactions. We have localized TGF-beta1 by molecular and immunohistochemical analysis in the developing mouse prostate. Acc...

journal_title：World journal of urology

authors： Timme TL,Yang G,Truong LD,Kadmon D,Park SH,Thompson TC

更新日期：1995-01-01 00:00:00

abstract：:Epidermal growth factor (EGF) and transforming growth factor-alpha (TGF alpha) are two closely related peptides that interact with cell-surface epidermal growth factor receptors (EGFR) to induce receptor tyrosine phosphorylation and activation of intracellular signal-transduction pathways. EGF appears to be the predom...

journal_title：World journal of urology

authors： Sherwood ER,Lee C

更新日期：1995-01-01 00:00:00

abstract：:Transcutaneous application of low-frequency electric current in the treatment of partially or temporarily denervated striated muscles is widely used to prevent or treat muscular atrophy. Due to the high regenerative capacity of smooth-muscle cells, this approach should be beneficial in the treatment of diseases with s...

journal_title：World journal of urology

authors： Stief CG,Weller E,Noack T,Djamilian M,Meschi M,Truss M,Jonas U

更新日期：1995-01-01 00:00:00